This book provides easy consultation and guidance for an appropriate understanding and management of endotoxic shock. Endotoxic shock results from a severe, generalized inflammatory response induced by bloodstream infection with gram-negative bacteria. However, endotoxin-induced inflammatory activation may be disconnected by Gram-Negative threats (e.g. Gram-Positive and yeast infections) as well as occur in multiple clinical scenarios like post-cardiac arrest syndrome and trauma, possibly due to gut barrier dysfunction and consequent endotoxin translocation. The clinical management is structured focusing and dedicating a chapter for antibiotics, corticosteroids, volume support, vasoactive and cardiostimulating drug, coagulopathy and nutritional support. In addition, this book is remarkable because describing polymixin b hemoperfusion points out molecular interactions, and hydrodynamics of Sorption. Each section includes •) brief pathophysiology; •) principles of management; •) key messages. Readers can find updated tips related to the diagnosis and management of endotoxic shock with a multidisciplinary approach drawing a pathway from endotoxin structure and source and the related pathophysiology of endotoxic shock underling the specific clinical aspect and focusing on medical clinical management of endotoxemia and extracorporeal removal. | |||
Table of contents : |
Endotoxin Induced-Shock: a Multidisciplinary Approach in Critical Care
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- Title: Endotoxin Induced-Shock: a Multidisciplinary Approach in Critical Care
- Author: Silvia De Rosa, Gianluca Villa
- Publisher: Springer
- Publication: 2023
- Edition: – Edition
- Language: English
- Pages: 132
- Ebook: PDF
- File size: 4 MB
- ISBN Number: 9783031185908
- CBID: CBM161
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