Patient Education
5′-Nucleotidase Test
Why am I having this test?
The 5′-nucleotidase test is used along with other liver function tests to determine if you have liver or gallbladder problems.
What is being tested?
This test measures the amount of 5′-nucleotidase in your blood. 5′-nucleotidase is a protein that is produced by the liver. The level of this protein is raised (elevated) in people who have liver disease.
What kind of sample is taken?
A blood sample is required for this test. It is usually collected by inserting a needle into a blood vessel.
How do I prepare for this test?
Follow instructions from your health care provider about eating or drinking restrictions before the test. Stop taking certain medicines before your blood test, as told by your health care provider.
Tell a health care provider about:
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All medicines you are taking, including vitamins, herbs, eye drops, creams, and over-the-counter medicines.
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Any medical conditions you have.
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Whether you are pregnant or may be pregnant.
How are the results reported?
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0–1.6 units at 37°C.
What do the results mean?
A 5′-nucleotidase level that is higher than the normal reference range may be a sign of liver disease.
Talk with your health care provider about what your results mean.
Questions to ask your health care provider
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When will my results be ready?
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How will I get my results?
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What are my treatment options?
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What other tests do I need?
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What are my next steps?
Summary
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The 5′-nucleotidase test is used along with other liver function tests to determine if you have liver or gallbladder problems.
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This test measures the amount of a liver protein called 5′-nucleotidase, which is usually elevated in people with liver disease.
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Results that are higher than the normal reference range may indicate liver disease.
This information is not intended to replace advice given to you by your health care provider. Make sure you discuss any questions you have with your health care provider.
