Acetaminophen; Dextromethorphan; Doxylamine Oral Solution

What is this medication?

ACETAMINOPHEN; DEXTROMETHORPHAN; DOXYLAMINE (a set a MEE noe fen; dex troe meth OR fan; dox IL a meen) is a combination of a pain reliever, a cough suppressant, and an antihistamine. It is used to treat the aches and pains, cough, fever, headache, runny nose, and sneezing of a cold. This medicine will not treat an infection.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

COMMON BRAND NAME(S): All-Nite, All-Nite Multi-Symptom, Contac Cold + Flu, Coricidin HBP Nighttime, Delsym NightTime Cough & Cold, Nite-Time Cold/Flu Relief, Tylenol Cough and Sore Throat Nighttime, Tylenol Warming Cough and Sore Throat Nighttime, Vicks Nature Fusion Cold & Flu, Vicks Nyquil Cold & Flu, Vicks NyQuil Nature Fusion, Zicam Flu Nighttime

What should I tell my care team before I take this medication?

They need to know if you have any of these conditions:

  • asthma, bronchitis, or other lung disease
  • cough that does not go away
  • cough with a lot of phlegm
  • glaucoma
  • if you often drink alcohol
  • liver disease
  • phenylketonuria
  • taken a MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
  • trouble passing urine
  • an unusual or allergic reaction to acetaminophen, dextromethorphan, doxylamine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medication?

Take this medicine by mouth. Follow the directions on the package label. Use a specially marked spoon or container to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take your medicine at regular intervals. Do not take it more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medication?

Do not take this medicine with any of the following medications:

  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

This medicine may also interact with the following medications:

  • alcohol
  • furazolidone
  • imatinib
  • isoniazid
  • linezolid
  • other medicines for cold, cough or allergy
  • other medicines with acetaminophen
  • procarbazine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medication?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Let your doctor know if the pain or cough gets worse or lasts for more than 7 days. Call your doctor if a fever gets worse or lasts for more than 3 days. If a cough does not go away, if a cough comes back, or if it occurs with a rah or headache see your doctor. Also see your doctor if a sore throat lasts more than 2 days or if it occurs with a fever, rash, headache, nausea, or vomiting.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

Do not take other medicines that contain acetaminophen with this medicine. Always read labels carefully. If you have questions, ask your doctor or pharmacist.

If you take too much acetaminophen get medical help right away. Too much acetaminophen can be very dangerous and cause liver damage. Even if you do not have symptoms, it is important to get help right away.

What side effects may I notice from receiving this medication?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • breathing problems
  • changes in vision
  • confusion
  • over excited, nervous, or restless
  • problems with balance, talking, walking
  • trouble passing urine or change in the amount of urine
  • unusual bleeding or bruising
  • unusually weak or tired
  • yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • drowsy, tired
  • headache
  • nausea, stomach upset

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medication?

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

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