Malignant peritoneal mesothelioma

Since Miller and Wayne reported the first case of peritoneal mesothelioma in 1908, cases have been reported successively. The incidence of peritoneal mesothelioma accounts for only 7 to 20% of mesothelioma, far lower than the incidence of pleura. Epidemiological studies have confirmed that exposure to asbestos is closely related to the incidence of malignant mesothelioma. However, unlike pleural mesothelioma, 80% of pleural mesothelioma was significantly associated with asbestos exposure, while only 8% of patients with malignant peritoneal mesothelioma (MPM) had a history of asbestos exposure, ^, suggesting that other factors such as chronic inflammatory peritonitis, carcinogenic viruses, etc. may cause the occurrence of MPM. MPM can occur at any age, the median age at diagnosis is mostly around 50, and it is more common in men. The clinical symptoms of MPM are very atypical and usually include abdominal pain, bloating, weight loss, ascites, and anorexia, and a few may manifest as unexplained, fever, microcirculatory hypercoagulable state, and intestinal obstruction. Nonspecific clinical manifestations may pose challenges to doctors in its diagnosis, especially in the absence of risk factors. In this paper, we report a case of MPM where the patient’s medical history did not indicate any exposure to asbestos or other risk factors.